The relationship between weight status and metabolic syndrome in patients with rheumatoid arthritis and spondyloarthritis

To compare the prevalence and correlates of metabolic syndrome (MetS) stratified by body mass index (BMI) categories in rheumatoid arthritis (RA) spondyloarthritis (SpA). The age- sex-standardized MetS was calculated BMI compared between RA SpA patients before starting first biologic, controls. determinants without obesity were investigated. observed 28% (21/75), 22.5% (18/80), 19% controls (187/998). not significantly different (95% CI: 11–27%), 26% 16–36%) 16% 14–18%). When BMI, standardized less frequent obese (15%, 95% 4–27%) to (48%, 40–55%) or (36%, 26–45%). In normal-weight patients, 7–25%) 5% 0–11%) SpA, 6% 4–8%) non-obese associated with abdominal obesity, visceral fat cardiovascular risk. syndrome, composition did differ from metabolically healthy patients. is uniform among similar BMI. RA, unlike Differences for health suggest various pathophysiological mechanisms.